منابع مشابه
Loratadine- Loaded Thermoresponsive Hydogel : Characterization and Ex-vivo Rabbit Cornea Permeability Studies
Poor bioavailability of ophthalmic drops is mainly due to drainage through the nasal-lacrimal duct and a very low permeability through corneal epithelium. The aim of our study was to prepare and characterize an ocular hydrogel of loratadine, as an example of a lipophilic drug, to increase drug concentration and residence time at the site of action in the eye. In this study,a 23full factorial de...
متن کاملLoratadine- Loaded Thermoresponsive Hydogel : Characterization and Ex-vivo Rabbit Cornea Permeability Studies
Poor bioavailability of ophthalmic drops is mainly due to drainage through the nasal-lacrimal duct and a very low permeability through corneal epithelium. The aim of our study was to prepare and characterize an ocular hydrogel of loratadine, as an example of a lipophilic drug, to increase drug concentration and residence time at the site of action in the eye. In this study,a 23full factorial de...
متن کاملAn Inexpensive Ex-Vivo Porcine Laparoscopic Nissen Fundoplication Training Model
BACKGROUND We recently implemented the use of an ex-vivo porcine model to teach residents the fundamentals of performing a laparoscopic Nissen fundoplication. METHODS Residents were trained using intact porcine esophagus, stomach, and spleen placed in a standard video-trainer. They were later asked to complete a survey containing a course evaluation. RESULTS Sixteen residents (R1-R4) comple...
متن کاملAn ex-vivo model for evaluating bioenergetics in aortic rings
Cardiovascular disease (CVD) is the leading cause of death worldwide and it exhibits a greatly increasing incidence proportional to aging. Atherosclerosis is a chronic condition of arterial hardening resulting in restriction of oxygen delivery and blood flow to the heart. Relationships between mitochondrial DNA damage, oxidant production, and early atherogenesis have been recently established a...
متن کاملChoroid Sprouting Assay: An Ex Vivo Model of Microvascular Angiogenesis
Angiogenesis of the microvasculature is central to the etiology of many diseases including proliferative retinopathy, age-related macular degeneration and cancer. A mouse model of microvascular angiogenesis would be very valuable and enable access to a wide range of genetically manipulated tissues that closely approximate small blood vessel growth in vivo. Vascular endothelial cells cultured in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: MethodsX
سال: 2020
ISSN: 2215-0161
DOI: 10.1016/j.mex.2020.100876